Zyris Isolite® Mouthpieces
Easy-to-use posterior and anterior mouthpieces for superior isolation to ensure patient comfort and better clinical outcomes.
Buy MouthpiecesThe brilliance of an Isolite System is in the mouthpiece! The patented and proprietary design of our Isolation Mouthpieces are the heart of our Award-Winning Dental Isolation Systems and the reason we are the Most Trusted Name in Dental Isolation!
Gain more control of the oral environment with the Zyrils Isolite two-quadrant and pre-molar to pre-molar mouthpieces.
- Dual-Channel Suction Control with continuous hands-free saliva and water evacuation
- Tongue and cheek retraction for ideal access and control
- Integrated bite block and airway protection for patient comfort and safety


Zyris Isolite Mouthpieces were developed to deliver superior Isolation and access for both Posterior and Anterior procedures with patient safety and comfort in mind.
You’ll love our Mouthpiece Size Selection - a Perfect Fit Every Time!
6 size options for a truly comfortable patient experience with every procedure.
Comprehensive Isolation and Access
Isolite provides continuous, hands-free isolation of both quadrants in the operative field. This means you can focus entirely on the procedure at hand, reducing fatigue and improving precision
- 360-degree isolation coverage ensures a consistently dry field throughout the entire procedure
- Flexible mouthpiece design adapts to individual patient anatomy for a comfortable, secure fit
- Integrated tongue and cheek retraction eliminates the need for additional retraction devices.
Dual-Channel High Volume Suction
Say goodbye to the constant battle against saliva, ensuring a dry field throughout your procedure.
- Removes fluids from both sides of the mouth simultaneously, utilizing the integrated bite block with rear suction port to significantly reduce pooling in patients’ mouths
- Two adjustable levers allow you to control the dual-channel suction for upper and lower simultaneously and independently
- Specifically designed to reduce patient sensitivity or discomfort from unneeded suction, while also minimizing noise for a more pleasant patient experience
Superior Isolation and Access with Uncompromised Patient Safety
- The only mouthpiece on the market with two channels of continuous hands-free vacuum suction and isolation so you can better control moisture, humidity and the oral environment.
- An integrated bite block to comfortably stabilize the patient’s mouth with 6 size options for a truly comfortable patient experience with every procedure
- Evacuation at the rear of bite block to reduce pooling in the patient’s mouth
- Cheek, tongue and throat shields to protect patients from injury
- Airway protection from debris
- 100% Clean Guaranteed
*With patient safety at the forefront, we take every precaution to make sure there are ZERO cross-contamination opportunities while using the Isolite system and every one of our single-use mouthpieces are 100% Clean Guaranteed! Isolite Mouthpieces were designed to be single-use with your patients safety in mind.
What clinicians across various specialties have to say about Isolite
“It saves me 30% in chair time and my production has increased so much since I’ve been using Isolite”.
-Dr. Jane Arena DDS
“The Isolite system is definitely one of the best inventions in dentistry. It’s made not only my job easier, but patients love it and so does my assistant”.
-Daniel Aneszko, DDS
“If you want to improve your dentistry, that’s the biggest thing, it provides quality all the time, again I’m miserable without it”.
-Dr. Brian Buehler, DDS
“Isolite gives you a nearly perfect amount of dryness in the mouth and enables our visibility to be excellent”.
-Dr. Michele Kaider-Alstodt
“Isolite for me is an essential tool for every dental practice – It allows me and my assistants to be as efficient as we can be”.
-Dr. Domenic Aloise
Isolite Posterior Mouthpieces
With 6 sizes to fit a wide range of patients, Zyris posterior mouthpieces provide dual-quadrant access and better visibility. Our integrated bite block provides patient comfort with rear evacuation to significantly reduce pooling in the patient’s mouth.


See our Posterior Mouthpieces in action:
Isolite Anterior Mouthpieces
For anterior procedures crossing the midline, the anterior mouthpiece provides pre-molar to pre-molar access.


See our Anterior Mouthpieces in action:
Instructions for Isolite Mouthpiece Sizing and Placement
The best way to ensure success and patient compliance with the Isolite Mouthpiece is to understand the correct sizing and placement technique.